Nucleotide excision repair
PAG Title | Nucleotide excision repair |
PAG ID | WIG001820 |
Type | P |
Source Link | Spike |
Publication Reference | NA |
PAG Description | Nucleotide excision repair (NER) is a particularly important mechanism by which the cell can prevent unwanted mutations by removing the vast majority of UV-induced DNA damage (mostly in the form of thymine dimers and 6-4-photoproducts). NER can be divided into two subpathways (Global genomic NER and Transcription coupled NER) that differ only in their recognition of helix-distorting DNA damage. |
Species | Homo sapiens |
Quality Metric Scores | nCoCo Score: 2,116 |
Information Content | Rich |
Other IDs | SPIKE00005 |
Base PAG ID | WIG001820 |
Human Phenotyte Annotation | |
Curator | PAGER curation team |
Curator Contact | PAGER-contact@googlegroups.com |
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